A Transport Vehicle‐enabled TREM2 agonist antibody induces putative transcription factor activation in microglia

Our data provide insights into putative transcription factors that mediate microglial state changes in response to ATV:4D9, which further elucidates mechanisms of TREM2 agonism.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2024-12-01
DOI
https://doi.org/10.1002/alz.090395
Primary Topic
Inflammation biomarkers and pathways
Type
article
Field-Weighted Citation Impact
0.00
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article

A Transport Vehicle‐enabled TREM2 agonist antibody induces putative transcription factor activation in microglia

Kathryn M. Monroe
Alzheimer s & Dementia
Inflammation biomarkers and pathways
article

A Transport Vehicle‐enabled TREM2 agonist antibody induces putative transcription factor activation in microglia

Kathryn M. Monroe
article en

Abstract

Our data provide insights into putative transcription factors that mediate microglial state changes in response to ATV:4D9, which further elucidates mechanisms of TREM2 agonism.

Alzheimer s & DementiaVol. 20(S1)
Denali Therapeutics (United States) (US)
Openalex Percentile: Top 69%
Inflammation biomarkers and pathways
DOIOpen Access PDFOpenAlex
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A Transport Vehicle‐enabled TREM2 agonist antibody induces putative transcription factor activation in microglia — Kathryn M. Monroe · Alzheimer s & Dementia (2024) | TGRS Research Map | TGRS