AD pathology‐independent effects of astrocyte‐ or microglia‐specific replacement of APOE4 with APOE2
Glial cell-specific expression of E2 alters microglia reactivity in response to various pathological challenges, including aging, inflammatory stimuli, and demyelination.
Authors
- E.M. Woodward
- Lance A. Johnson (ORCID: https://orcid.org/0000-0003-0134-7586)
- Lesley R. Golden (ORCID: https://orcid.org/0000-0001-8922-8850)
- Josh M. Morganti (ORCID: https://orcid.org/0000-0002-4183-0049)
- Steven M. MacLean (ORCID: https://orcid.org/0000-0003-1359-6731)
- Gabriela Hernandez (ORCID: https://orcid.org/0000-0002-3857-2659)
- Georgia L. Nolt
- Joshua Moses
- Isaiah O. Stephens (ORCID: https://orcid.org/0009-0007-7070-1805)
- Dahlia Siano
Institutions
- University of Kentucky (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1002/alz.091247
- Primary Topic
- Chemokine receptors and signaling
- Type
- article
- Field-Weighted Citation Impact
- 0.00