Transmission of Alzheimer’s disease‐associated microbiota dysbiosis and its impact on cognitive function: evidence from mice and patients

This initial proof-of-concept study demonstrated the potential transmission of microbiota from AD patients or ADTg mice to non-AD controls or WT mice housed together. This transmission may contribute to the development of AD-associated microbiota dysbiosis and metabolite alterations, ultimately leading to AD pathogenesis and cognitive impairment. However, these findings should be validated in future studies. The results of this study are expected to drive further research to explore gut microbiota dysbiosis and its connection to AD in both preclinical and clinical contexts.