Cholinergic white matter pathways in Alzheimer’s disease, dementia with Lewy bodies, and other neurodegenerative diseases: a post‐mortem MRI study
We expanded previous in-vivo MRI findings to post-mortem MRI and confirmed the degeneration of cholinergic WM pathways in AD. Additionally, we highlighted the difference between AD and LBD donors, with a more severe cholinergic pathway degeneration in AD donors. References: 1. Schumacher J, et al. Cholinergic WM pathways in dementia with Lewy bodies and AD. Brain. 2022 Jun 3;145(5):1773-1784.
Authors
- Michel J. Grothe (ORCID: https://orcid.org/0000-0003-2600-9022)
- Francisco Javier López‐González (ORCID: https://orcid.org/0000-0001-8990-0344)
- Daniel Ferreira (ORCID: https://orcid.org/0000-0001-9522-4338)
- Milan Němý (ORCID: https://orcid.org/0000-0002-4870-1354)
- Pascual Sánchez‐Juan
- Alberto Rábano
Institutions
- Instituto de Salud Carlos III (ES)
- Karolinska Institutet (SE)
- Fundacion Centro De Investigacion De Enfermedades Neurologicas (ES)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1002/alz.089110
- Primary Topic
- Advanced Neuroimaging Techniques and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00