Deep Learning Model for Forecasting Propagation of Amyloidopathy in Alzheimer’s Disease

We introduced a deep learning model that simulates the diffusion of amyloid-β with strong predictive performance and interpretation. While parameters were optimized for the entire group, accuracy varied for some subjects. Also, further investigation is needed to interpret each term comprehensively. Despite the need for individual optimization and additional interpretative analysis, the model may contribute to the diagnosis of AD.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2024-12-01
DOI
https://doi.org/10.1002/alz.085828
Primary Topic
Alzheimer's disease research and treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Deep Learning Model for Forecasting Propagation of Amyloidopathy in Alzheimer’s Disease

Hyun‐Ghang Jeong, Cheol E. Han, ByeongChang Jeong, Surin Seo et al.
Alzheimer s & Dementia
Alzheimer's disease research and treatments
article

Deep Learning Model for Forecasting Propagation of Amyloidopathy in Alzheimer’s Disease

Hyun‐Ghang Jeong, Cheol E. Han, ByeongChang Jeong, Surin Seo, Seung‐Hoon Lee, Daegyeom Kim
article en

Abstract

We introduced a deep learning model that simulates the diffusion of amyloid-β with strong predictive performance and interpretation. While parameters were optimized for the entire group, accuracy varied for some subjects. Also, further investigation is needed to interpret each term comprehensively. Despite the need for individual optimization and additional interpretative analysis, the model may contribute to the diagnosis of AD.

Alzheimer s & DementiaVol. 20(S1)
Korea University (KR), Korea University Medical Center (KR), Sejong University (KR)
Good health and well-being
Openalex Percentile: Top 65%
Alzheimer's disease research and treatments
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