SMOC1 colocalizes with Alzheimer’s disease neuropathology and delays Aβ aggregation
SMOC1 colocalizes with amyloid plaques, CAA and tau pathology. SMOC1 interacts with Aβ and delays Aβ aggregation in vitro, making it a key candidate for future drug development studies.
Authors
- Tomas Kavanagh (ORCID: https://orcid.org/0000-0003-2184-3552)
- Margaret Sunde (ORCID: https://orcid.org/0000-0002-0150-3203)
- Glenda Margaret Halliday (ORCID: https://orcid.org/0000-0003-0422-8398)
- Thomas Wısnıewskı (ORCID: https://orcid.org/0000-0002-3379-8966)
- Eleanor Drummond (ORCID: https://orcid.org/0000-0002-5466-4609)
- Caitlin Johnston (ORCID: https://orcid.org/0000-0003-1383-6731)
- Kaleah Balcomb (ORCID: https://orcid.org/0009-0003-7006-2776)
Institutions
- The University of Sydney (AU)
- New York University (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1002/alz.090551
- Primary Topic
- Alzheimer's disease research and treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00