Large‐scale exome sequencing identifies novel genes for socioeconomic status, education, and cognition

This study utilizes large-scale exome sequencing to provide a more comprehensive genetic framework underlying SES/EA/Cognition, offering informative associated genes and biological insights. The identified 79 genes across full allele frequency spectrum, 64 of which exhibited novel associations, would provide an abundant resource for further in-depth molecular mechanistic studies and drug development for cognition.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2024-12-01
DOI
https://doi.org/10.1002/alz.088059
Primary Topic
Genomics and Rare Diseases
Type
article
Field-Weighted Citation Impact
0.00
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article

Large‐scale exome sequencing identifies novel genes for socioeconomic status, education, and cognition

Xiaohui Wu, Jin‐Tai Yu
1 links
Alzheimer s & Dementia
Genomics and Rare Diseases
article

Large‐scale exome sequencing identifies novel genes for socioeconomic status, education, and cognition

Xiaohui Wu, Jin‐Tai Yu
article en

Abstract

This study utilizes large-scale exome sequencing to provide a more comprehensive genetic framework underlying SES/EA/Cognition, offering informative associated genes and biological insights. The identified 79 genes across full allele frequency spectrum, 64 of which exhibited novel associations, would provide an abundant resource for further in-depth molecular mechanistic studies and drug development for cognition.

Alzheimer s & DementiaVol. 20(S1)
Fudan University (CN), Huashan Hospital (CN)
Quality Education
Openalex Percentile: Top 73%
Genomics and Rare Diseases
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