Validation of Various Pan‐ApoE and Isoform‐Specific ApoE Antibodies

These data identify several isoform-specific ApoE antibodies that are reliable and selective across multiple sample types and applications; albeit some display higher affinity for one application over another. Overall, we hope these results will provide AD researchers with important resources that are crucial for visualizing and quantifying ApoE isoform distribution in heterozygote individuals and across a number of AD models, systems, and studies.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2024-12-01
DOI
https://doi.org/10.1002/alz.091634
Primary Topic
Computational Drug Discovery Methods
Type
article
Field-Weighted Citation Impact
0.00
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article

Validation of Various Pan‐ApoE and Isoform‐Specific ApoE Antibodies

Lance A. Johnson, Lesley R. Golden, Steven M. MacLean, Gabriela Hernandez et al.
Alzheimer s & Dementia
Computational Drug Discovery Methods
article

Validation of Various Pan‐ApoE and Isoform‐Specific ApoE Antibodies

Lance A. Johnson, Lesley R. Golden, Steven M. MacLean, Gabriela Hernandez, Dahlia Siano
article en

Abstract

These data identify several isoform-specific ApoE antibodies that are reliable and selective across multiple sample types and applications; albeit some display higher affinity for one application over another. Overall, we hope these results will provide AD researchers with important resources that are crucial for visualizing and quantifying ApoE isoform distribution in heterozygote individuals and across a number of AD models, systems, and studies.

Alzheimer s & DementiaVol. 20(S1)
University of Kentucky (US)
Good health and well-being
Openalex Percentile: Top 71%
Computational Drug Discovery Methods
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