IMPACT OF THE USE OF LIDOCAINE AND MAGNESIUM SULFATE AS ANESTHETIC ADJUVANTS ON POSTOPERATIVE PAIN

Local anesthetics such as lidocaine and NMDA receptor antagonists, like magnesium sulfate, have shown promise in the management of acute pain, offering antinociceptive, antihyperalgesic, and anti-inflammatory properties. However, despite being accessible and economically viable solutions, there are still gaps in knowledge. In this context, this study aims to review the scientific literature on the impact of using lidocaine and magnesium sulfate as adjuvants during anesthesia on postoperative pain intensity. The methodology of this study consisted of a narrative literature review, aimed at evaluating the effectiveness of analgesia using lidocaine and magnesium sulfate in reducing postoperative pain. To ensure the quality of the review, the SANRA (Scale for the Quality Assessment of Narrative Review Articles) was applied. The selection of articles was carried out through searches in the Pubmed (Medline), Embase, and Web of Science databases. Only full-text articles published in the last ten years were included, ensuring the relevance and timeliness of the evidence analyzed. Based on the analysis of the available studies, it can be concluded that, although lidocaine and magnesium sulfate show potential as effective adjuvants in perioperative analgesia, further research is needed to confirm their efficacy and safety.