Operative management of breast cancer patients according to the clinicopathological characteristics at Dr. Kariadi General Hospital, Semarang 2020-2022

Background: Breast cancer is a malignancy that attacks breast tissue, both the ductal epithelium and breast lobules. Treatment that can be given to breast cancer patients is surgery (surgery), chemotherapy, radiation therapy, and hormonal therapy. This study aims to evaluate the operative management of breast cancer patients according to the clinicopathological characteristics at Dr. Kariadi General Hospital, Semarang 2020-2022. Methods: A descriptive study with a cross-sectional approach among 45 patients was conducted at Dr. Kariadi General Hospital from February to March 2024 with a total sampling technique. Variables assessed in this study include age, gender, Body Mass Index (BMI), histopathology characteristics, grade of differentiation, stage, immunohistochemistry subtype, and operative management. Data were analysed using SPSS version 25.0 for Windows. Results: Most of the respondents 41-50 years age group (37.8%), followed by females (100.0%), obesity type II (51.1%), invasive ductal carcinoma (60.0%), grade 2 differentiation (82.2%), Stage II (A and B) (68.9%), Luminal B-type breast cancer (42.2%), and modified radical mastectomy (60.0%) as operative management. Modified radical mastectomy was the predominant operative management in the invasive ductal carcinoma (40.0%), grade 2 (42.2%), stage III (A, B, and C) (31.1%), and Luminal B subtypes (26.6%) of cancer. Conclusion: Modified radical mastectomy was the predominant operative management based on the histopathology of invasive ductal carcinoma, grade 2, stage III (A, B, and C), and Luminal B subtypes of cancer.