Mesenchymal stem cells for treatment of liver cirrhosis

Background: Liver cirrhosis is caused by long-term liver damage, leading to scar tissue buildup. It often results from viral infections or excessive alcohol use. The disease is usually asymptomatic and found during check-ups, but severe cases can cause liver failure and portal hypertension. Treatment options are limited, with liver transplantation being the only way to improve survival, though it carries risks of rejection and high costs. Case Presentation: Male patient, 50 years old, with the initials IDP, experiences intermittent abdominal pain and nausea. Physical examination shows moderate health, weight 69 kg, blood pressure 120/80 mmHg, pulse rate 81 bpm, respiratory rate 20 breaths per minute, and axillary temperature 37°C. Pain in the epigastric area is rated 3 out of 10. There is a protrusion in the abdomen and pain in the upper middle and upper left areas of the abdomen. Percussion of the abdomen shows positive undulation, positive shifting dullness, and dull sound in Traube's space. Laboratory tests show elevated levels of total bilirubin, direct bilirubin, indirect bilirubin, SGOT, and SGPT. HBsAg test is positive with a value of 6.83 IU/ml. Conclusion: Preclinical and clinical research investigating the use of stem cell therapy for the treatment of cirrhosis has yielded promising results.