Evaluation of a nanostructured CpG-ODN/ascorbyl palmitate as a safe and effective adjuvant for anticrotalic PLA2 serum
The Coa-ASC16/CpG-ODN formulation shows promise as a safe and effective adjuvant against crotalic PLA2, inducing a strong humoral response and reducing local tissue damage compared with Freund's adjuvant.
Authors
- Yvelise Barrios-A. Franco
- Laura Leiva (ORCID: https://orcid.org/0000-0002-3468-6499)
- David Roque Hernández (ORCID: https://orcid.org/0000-0001-8375-3021)
- Constanza Marín (ORCID: https://orcid.org/0000-0002-3872-8086)
- Belkys Angélica Maletto (ORCID: https://orcid.org/0000-0002-8211-4364)
- Andrea Van de Velde
- Gabriel Morón (ORCID: https://orcid.org/0000-0003-2122-6730)
- María G. Cháves (ORCID: https://orcid.org/0000-0002-5401-2264)
- Luciano Fusco (ORCID: https://orcid.org/0000-0002-7784-6237)
- Sofía Gisella Brignone (ORCID: https://orcid.org/0000-0002-5472-6224)
- Juan J. Calvete (ORCID: https://orcid.org/0000-0001-5026-3122)
- Santiago D. Palma
- Franco Maslovski
- Gisela Lumila Lopez
Institutions
- Consejo Nacional de Investigaciones Científicas y Técnicas (AR)
- Universidad Nacional de Córdoba (AR)
- National University of the Northeast (AR)
- Centro Científico Tecnológico - Nordeste (AR)
- Research Centre in Biological Chemistry of Córdoba (AR)
- Instituto de Química del Noroeste Argentino (AR)
- Instituto de Biomedicina de Valencia (ES)
Publication Details
- Journal
- Transactions of the Royal Society of Tropical Medicine and Hygiene
- Published
- 2024-11-30
- DOI
- https://doi.org/10.1093/trstmh/trae129
- Citations
- 2
- Primary Topic
- Venomous Animal Envenomation and Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.10
Funders
- Universidad Nacional del Nordeste
- Agencia Nacional de Promoción Científica y Tecnológica