BRCA testing in metastatic castration-resistant prostate cancer: successes and troubles in a real world setting. An Italian Multicentric study

Excessive FFPE tissues storage time (more than 3 years) can harshly affect DNA analysis and evaluability, hindering the achievement of a result useful in the clinical practice. Hence, it should be considered to perform the analysis as soon as possible to increase the evaluability of the test.

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Publication Details

Journal
Pathologica
Published
2024-10-01
DOI
https://doi.org/10.32074/1591-951x-1010
Citations
2
Primary Topic
Prostate Cancer Treatment and Research
Type
article
Field-Weighted Citation Impact
0.84
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article

BRCA testing in metastatic castration-resistant prostate cancer: successes and troubles in a real world setting. An Italian Multicentric study

Elisa Melucci, Gabriella Cirmena, Stefania Tommasi, Matteo Corsi et al.
2 citations
Pathologica
Prostate Cancer Treatment and Research
0.84
article

BRCA testing in metastatic castration-resistant prostate cancer: successes and troubles in a real world setting. An Italian Multicentric study

Elisa Melucci, Gabriella Cirmena, Stefania Tommasi, Matteo Corsi, Gabriella Fontanini, Sergio Vincenzo Taormina, Beatrice Casini, Massimo Barberis, Davide Vacirca, Giancarlo Troncone, Michele Paudice, Pinuccia Faviana, Mariantonia Carosi, Viviana Gismondi, Francesco Alfredo Zito, Rossella Bruno, Alessandro Caniglia, Brunella Pilato, Sergio Bracarda, Cecilia Caprera, Francesco Pepe, Simona Francesconi, Andrea Russo, Umberto Malapelle, C. Coppola
article en
2 citations

Abstract

Excessive FFPE tissues storage time (more than 3 years) can harshly affect DNA analysis and evaluability, hindering the achievement of a result useful in the clinical practice. Hence, it should be considered to perform the analysis as soon as possible to increase the evaluability of the test.

PathologicaVol. 116(5)
University of Perugia (IT), Istituto Nazionale di Fisica Nucleare, Sezione di Napoli (IT), Istituto Oncologico Veneto (IT), Azienda Ospedaliera S.Maria (IT), Istituto Tumori Bari (IT), Tumori Foundation (US), Ospedale Policlinico San Martino (IT), Azienda Ospedaliera Universitaria Pisana (IT), European Institute of Oncology (IT), University of Naples Federico II (IT)
Good health and well-being
Openalex Percentile: Top 22%
Prostate Cancer Treatment and Research
0.84
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