Low-grade endometrial endometrioid carcinoma of the p53-abnormal group: case presentation and diagnostic issues
A glandular neoplasm with p53 and/or p16-overexpression on endometrial biopsy specimens may raise the concern of other entities such as serous carcinoma, HPV-related endocervical adenocarcinoma, and gastric-type adenocarcinoma. An immunohistochemical panel including hormone receptors, p53, p16 and mismatch repair proteins appears necessary for an accurate diagnosis of uterine adenocarcinomas.
Authors
- Eleonora Di Lauro
- Giuseppe Angelico (ORCID: https://orcid.org/0000-0003-4808-2052)
- Susanna Ronchi
- Carla Facco
- Stefano La Rosa (ORCID: https://orcid.org/0000-0003-1941-2403)
- Angela Santoro (ORCID: https://orcid.org/0000-0002-6964-5152)
- Damiano Arciuolo (ORCID: https://orcid.org/0000-0002-3927-985X)
- Jvan Casarin (ORCID: https://orcid.org/0000-0001-9519-1097)
- Gian Franco Zannoni (ORCID: https://orcid.org/0000-0002-4473-7560)
- Caterina Fulgione
- Antonio Raffone (ORCID: https://orcid.org/0000-0001-5443-2333)
- Antonio Travaglino (ORCID: https://orcid.org/0000-0003-4002-1618)
Institutions
- Università Cattolica del Sacro Cuore (IT)
- University of Insubria (IT)
- Agostino Gemelli University Polyclinic (IT)
- University of Catania (IT)
- Aziende Socio Sanitarie Territoriale dei Sette Laghi
- University of Naples Federico II (IT)
- University of Bologna (IT)
Publication Details
- Journal
- Pathologica
- Published
- 2024-10-01
- DOI
- https://doi.org/10.32074/1591-951x-1044
- Primary Topic
- Endometrial and Cervical Cancer Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00