Hormonal and metabolic profiles and their association with BMI in Iraqi women with Polycystic Ovary Syndrome

Polycystic ovary syndrome (PCOS) is a problem with hormones that occurs during the reproductive years. If you have PCOS, you may not have your period very often. Or you may have periods that last many days. You may also have too much of a hormone called androgen in your body. This study included a sample of 35 Iraqi women who had been diagnosed with polycystic ovary syndrome (PCOS), and a control group of 35 healthy individuals. Anthropometric measurements, such as body mass index (BMI) and waist-to-hip ratio (WHR), were documented. Hormonal and metabolic profiles were examined in blood samples from all participants. The statistical analysis system (SPSS) version 28 was used to calculate mean ± SD and p-value. LH, LH/FSH ratio and BMI levels were significantly higher in obese PCOS patients compared to control subjects. In addition, the study showed an LH/FSH ratio level of 0.5774±0.9221 for the control groups and 1.0061±0.310 for the POCS groups. The insulin level was 7.874±0.6978 for the control groups and 27.07±6.354 for the POCS groups. The estrogen level was 58.62 ± 27.32 for the control groups and 78.20 ± 32.4 for the POCS group. All the results of LH/FSH ratio, progesterone, prolactin, testosterone, estrogen, insulin, and Zn were significantly higher in obese PCOS compared to the control group. Although adropin contributes to better health regulation compared to women with PCOS, its impact was less pronounced in women with PCOS.