Atrophy Network Mapping of Anxiety in Cognitively Unimpaired Older Adults in Preclinical AD
We identified a brain network associated with anxiety symptoms in cognitively unimpaired older adults with elevated amyloid-β. These findings help elucidate a neuropathophysiology of anxiety in preclinical AD and, possibly, its role in disease progression. The brain network identified in this project could yield new neurostimulation targets for anxiety in older adults across the AD continuum.
Authors
- Shan H. Siddiqi (ORCID: https://orcid.org/0000-0002-0967-9289)
- Nancy J. Donovan (ORCID: https://orcid.org/0000-0002-6328-1589)
- Benjamin S. Zide (ORCID: https://orcid.org/0009-0003-5621-8850)
- Stephan Palm (ORCID: https://orcid.org/0009-0000-8345-5470)
- Michael Fox (ORCID: https://orcid.org/0000-0001-8848-6399)
- Soyoung Lee
- William J Drew
Institutions
- Brigham and Women's Hospital (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1002/alz.091060
- Primary Topic
- Functional Brain Connectivity Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00