Everyday life episodic memory change and limbic quantitative PI‐2620 tau PET in participants with mild cognitive impairment and mild dementia
In participants with Alzheimer's pathologic change, we found a significant correlation between episodic memory impairment and tau abnormality in Braak stage 3 regions, which encompass critical elements of the Papez circuit. The results suggest that EMCS could serve as a practical and easily accessible tool for early detection of tau PET positivity in A+ individuals, offering a straightforward approach for identifying Alzheimer's-related tau changes in a timely manner.
Authors
- Chanan Sukprakun (ORCID: https://orcid.org/0000-0001-9128-8000)
- Akarin Hiransuthikul (ORCID: https://orcid.org/0000-0003-1906-8171)
- Kittithatch Booncharoen
- Yuttachai Likitjaroen (ORCID: https://orcid.org/0009-0009-7488-325X)
- Supatporn Tepmongkol (ORCID: https://orcid.org/0000-0002-6092-0488)
- Sekh Thanprasertsuk (ORCID: https://orcid.org/0000-0002-0267-1372)
- Kammant Phanthumchinda (ORCID: https://orcid.org/0000-0001-6032-3336)
- Poosanu Thanapornsangsuth (ORCID: https://orcid.org/0000-0002-1317-9404)
Institutions
- Chulalongkorn University (TH)
- King Chulalongkorn Memorial Hospital (TH)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1002/alz.085860
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00