Computerized testing to detect cognitive decline in biomarker‐confirmed Alzheimer’s disease: Longitudinal findings from the ARMADA study.
The NIHTB detects cross-sectional impairment in episodic memory, attention, executive functions and working memory and longitudinal change in processing speed, working memory and auditory word comprehension in prodromal-to-mild AD. These findings further support the use of the NIHTB in AD research, but also imply that the optimal NIHTB composite to detect cognitive decline may differ across AD clinical stages.
Authors
- Sandra Weıntraub (ORCID: https://orcid.org/0000-0003-2605-5205)
- Hiroko H. Dodge (ORCID: https://orcid.org/0000-0001-7290-8307)
- Roos J. Jutten (ORCID: https://orcid.org/0000-0002-3712-4790)
- Emily Ho (ORCID: https://orcid.org/0000-0002-3522-3779)
- Carol A. Van Hulle (ORCID: https://orcid.org/0000-0002-2288-8819)
- Tatiana Karpouzian‐Rogers (ORCID: https://orcid.org/0000-0003-2902-5896)
- Richard C Gershon (ORCID: https://orcid.org/0000-0003-0085-0112)
- Cindy J. Nowinski (ORCID: https://orcid.org/0000-0001-5608-909X)
- Dorene M. Rentz (ORCID: https://orcid.org/0000-0002-6318-9213)
Institutions
- Northwestern University (US)
- Brigham and Women's Hospital (US)
- University of Wisconsin–Madison (US)
- Harvard University (US)
- Massachusetts General Hospital (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1002/alz.092380
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00