Cytoplasmic expression of TDP‐43 in aged mice display hippocampal sclerosis‐like degeneration and neuronal loss with reduced lifespan

This aged hippocampal sclerosis-like model may provide a greater understanding of the pathogenesis of neurodegeneration seen in TDP-43 proteinopathies.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2024-12-01
DOI
https://doi.org/10.1002/alz.090943
Primary Topic
Amyotrophic Lateral Sclerosis Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Cytoplasmic expression of TDP‐43 in aged mice display hippocampal sclerosis‐like degeneration and neuronal loss with reduced lifespan

Margaret E. Flanagan, Kaouther Ajroud, Matthew B Dopler, Jaclyn Lilek et al.
Alzheimer s & Dementia
Amyotrophic Lateral Sclerosis Research
article

Cytoplasmic expression of TDP‐43 in aged mice display hippocampal sclerosis‐like degeneration and neuronal loss with reduced lifespan

Margaret E. Flanagan, Kaouther Ajroud, Matthew B Dopler, Jaclyn Lilek, Ashley J. Anderson, Michael A. Gitcho, Sanaz Arezoumandan, Stephani A. Davis, Eva Bambakadis, Rachel Shapiro, Nigel J. Cairns, Damian Osei‐KanKam
article en

Abstract

This aged hippocampal sclerosis-like model may provide a greater understanding of the pathogenesis of neurodegeneration seen in TDP-43 proteinopathies.

Alzheimer s & DementiaVol. 20(S1)
Delaware State University (US), The University of Texas at San Antonio Health Science Center (US), University of Exeter (GB), University of Pennsylvania (US)
Openalex Percentile: Top 62%
Amyotrophic Lateral Sclerosis Research
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