Variable Sleep Quality Is Related to Tau Burden and Worse Memory in Older Women at Risk for Alzheimer’s Disease

Variability in sleep quality is associated with greater tau burden and worse memory function in older women at risk for AD, particularly among APOE-ε4 carriers. Results highlight the possibility that variable sleep quality is a modifiable risk factor in the early pathogenesis of AD and its cognitive sequelae.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2024-12-01
DOI
https://doi.org/10.1002/alz.090079
Primary Topic
Sleep and related disorders
Type
article
Field-Weighted Citation Impact
0.00
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Variable Sleep Quality Is Related to Tau Burden and Worse Memory in Older Women at Risk for Alzheimer’s Disease

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Variable Sleep Quality Is Related to Tau Burden and Worse Memory in Older Women at Risk for Alzheimer’s Disease

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article en

Abstract

Variability in sleep quality is associated with greater tau burden and worse memory function in older women at risk for AD, particularly among APOE-ε4 carriers. Results highlight the possibility that variable sleep quality is a modifiable risk factor in the early pathogenesis of AD and its cognitive sequelae.

Alzheimer s & DementiaVol. 20(S3)
San Diego State University (US), UC San Diego Health System (US), University of California San Diego (US)
Good health and well-being
Openalex Percentile: Top 69%
Sleep and related disorders
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