Diminished awareness, rather than hyperawareness, is more indicative for the progression along the Alzheimer’s clinical continuum, already in the subjective cognitive decline.
Unawareness of cognitive decline is related to a decreased risk of conversion to dementia in the clinical population. Specifically, in SCD, diminished awareness, rather than hyperawareness, is more indicative of progression to MCI. Informant reports and minor cognitive deficits in SCD provide valuable insights, emphasizing their importance in clinical settings and pharmacological trials.
Authors
- Emrah Düzel (ORCID: https://orcid.org/0000-0002-0139-5388)
- Enise I. Incesoy (ORCID: https://orcid.org/0000-0003-2014-4098)
Institutions
- German Center for Neurodegenerative Diseases (DE)
- Otto-von-Guericke-Universität Magdeburg (DE)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1002/alz.089973
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00