Influence of liver function on Alzheimer’s brain pathologies: A longitudinal study
The present findings, based on longitudinal observation for older adults, suggest that lower liver function may accelerate the accumulation of AD pathology in the brain. These results also support the possibility that the liver-brain axis could be a potential target for therapeutic or preventive strategies against AD.
Authors
- Yoon Young Chang (ORCID: https://orcid.org/0009-0006-0279-1880)
- Yu Kyeong Kim (ORCID: https://orcid.org/0000-0002-3282-822X)
- Gijung Jung (ORCID: https://orcid.org/0000-0001-5952-3373)
- Min Soo Byun (ORCID: https://orcid.org/0000-0003-3159-4510)
- Koung Mi Kang (ORCID: https://orcid.org/0000-0001-9643-2008)
- Yun‐Sang Lee
- Nayeong Kong
- Jee Wook Kim (ORCID: https://orcid.org/0000-0002-9570-4216)
- Dahyun Yi (ORCID: https://orcid.org/0000-0002-0860-0946)
- Chul‐Ho Sohn (ORCID: https://orcid.org/0000-0003-0039-5746)
- Jun‐Young Lee (ORCID: https://orcid.org/0000-0002-5893-3124)
- Dong Young Lee (ORCID: https://orcid.org/0000-0001-8976-8320)
- Joon Hyung Jung
- Hyejin Ahn (ORCID: https://orcid.org/0000-0002-5759-8969)
Institutions
- Seoul National University (KR)
- Seoul National University Hospital (KR)
- SNUH SMG-SNU Boramae Medical Center (KR)
- Inje University Sanggye Paik Hospital (KR)
- Hallym University Dongtan Sacred Heart Hospital (KR)
- Chungbuk National University Hospital (KR)
- Keimyung University (KR)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1002/alz.088641
- Primary Topic
- Alzheimer's disease research and treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00