Psychological profiles associated with cortical thickness changes in middle‐aged adults
Using a person-centered approach to identify statistically distinct psychological profiles we found that already in middle-age, those with lower levels of protective factors (Profile 1) exhibit accelerated cortical atrophy. This emphasizes the need for comprehensive psychological assessments in dementia prevention research, including the assessment of 'protective' factors in addition to the more commonly assessed 'risk' factors.
Authors
- María Cabello‐Toscano (ORCID: https://orcid.org/0000-0001-5066-3476)
- Natalie L. Marchant (ORCID: https://orcid.org/0000-0003-0669-6910)
- Josep M. Tormos (ORCID: https://orcid.org/0000-0002-8764-2289)
- Núria Bargalló (ORCID: https://orcid.org/0000-0001-6284-5402)
- Lídia Vaqué‐Alcázar (ORCID: https://orcid.org/0000-0002-6776-6559)
- David Bartrés‐Faz (ORCID: https://orcid.org/0000-0001-6020-4118)
- Álvaro Pascual‐Leone (ORCID: https://orcid.org/0000-0001-8975-0382)
- Harriet Demnitz‐King (ORCID: https://orcid.org/0000-0002-7421-7101)
- Rob Saunders (ORCID: https://orcid.org/0000-0002-7077-8729)
- Gabriele Cattaneo (ORCID: https://orcid.org/0000-0002-7411-6829)
- Javier Solana Sánchez (ORCID: https://orcid.org/0000-0003-0880-7856)
Institutions
- Universitat Autònoma de Barcelona (ES)
- Hospital de Sant Pau (ES)
- Valencia Catholic University Saint Vincent Martyr (ES)
- Institut Guttmann (ES)
- Hospital Clínic de Barcelona (ES)
- Hebrew SeniorLife (US)
- Consorci Institut D'Investigacions Biomediques August Pi I Sunyer (ES)
- University College London (GB)
- Universitat de Barcelona (ES)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1002/alz.091151
- Citations
- 1
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.39