Exploring the differential impact of sociodemographic and extrinsic factors on mobility‐based digital phenotypes versus standard cognitive tests among older adults

Passively-obtained mobility phenotypes were significantly and moderately correlated with gold standard neuropsychological tests commonly used for clinical assessment and clinical trial endpoints. Several factors pertinent to social determinants of health were related to neuropsychological tests but not GPS features, suggesting naturalistic assessment via digital phenotyping may be less biased by these factors. On the other hand, other important factors including lifetime income and native English language impacted both methods of assessment.