Bias in estimating brain‐cognition associations by clinical diagnosis: A simulation study
Decisions about whether to stratify analyses by diagnostic subgroup require consideration of the target of inference. If the goal of cognitive aging research is to understand the cognitive manifestations of neurodegeneration across the full spectrum of disease, then subgroup analysis is likely to be more biased than the combined sample. With representative samples, both approaches may provide complementary information.
Authors
- Brandon E. Gavett (ORCID: https://orcid.org/0000-0003-1938-1854)
- Keith F. Widaman (ORCID: https://orcid.org/0000-0002-6424-3998)
- Dan Mungas (ORCID: https://orcid.org/0000-0003-2035-7085)
- Evan Fletcher
- Sarah Tomaszewski Farias (ORCID: https://orcid.org/0009-0009-8969-3387)
Institutions
- University of California, Riverside (US)
- University of California, Davis (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1002/alz.087815
- Citations
- 1
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.39