Visual imagery ability in the continuum of Alzheimer’s disease: the mind’s eye compared in patients with MCI and early AD
Our findings suggested that generation, inspection and transformation processes of VMI are impaired since the early phase of Alzheimer's disease. Moreover, we found that the generation process is selectively impaired in aMCI patients, demonstrating that VMI deficits are already present in the prodromal stage of the disease. Since alterations in VMI processing might reflect the AD neuropathological progression, according to Braak and Braak's model, VMI abilities might represent a useful neuropsychological marker of dementia to identify AD prodromal stage.
Authors
- Maddalena Boccia (ORCID: https://orcid.org/0000-0002-2044-8326)
- Giuseppe Bruno (ORCID: https://orcid.org/0000-0001-6948-7169)
- Emanuela Salati (ORCID: https://orcid.org/0000-0003-0029-0645)
- Cecilia Guariglia (ORCID: https://orcid.org/0000-0001-7474-6030)
- Fabrizia D’Antonio (ORCID: https://orcid.org/0000-0002-0898-5938)
- Antonella Di Vita (ORCID: https://orcid.org/0000-0003-2345-4809)
- Laura Piccardi (ORCID: https://orcid.org/0000-0002-1322-5538)
- Micaela Sepe‐Monti
- Giulia Bechi Gabrielli (ORCID: https://orcid.org/0000-0003-1653-3859)
- Roberta Margiotta (ORCID: https://orcid.org/0000-0002-0657-342X)
- Liana Palermo (ORCID: https://orcid.org/0000-0001-8047-7201)
- Giuseppina Talarico (ORCID: https://orcid.org/0000-0002-3608-087X)
- Massimiliano Panigutti
Institutions
- Magna Graecia University (IT)
- Sapienza University of Rome (IT)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1002/alz.092311
- Primary Topic
- Retinal Imaging and Analysis
- Type
- article
- Field-Weighted Citation Impact
- 0.00