Defining the role of perineuronal nets in Alzheimer’s disease pathology
Increases in plaque load and an impaired microglial response to plaques by 8 months in the PNN KO group suggest PNNs protect against plaque accumulation and appear to be essential for proper microglial response to plaques.
Authors
- Rocio A. Barahona (ORCID: https://orcid.org/0000-0003-1654-6377)
- Giovanna Rubio Salgado (ORCID: https://orcid.org/0000-0001-6921-8938)
- Kim N. Green
- Aashna R. Kono‐Soosaipillai
Institutions
- University of California, Irvine (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1002/alz.089449
- Primary Topic
- Proteoglycans and glycosaminoglycans research
- Type
- article
- Field-Weighted Citation Impact
- 0.00