‘Dependence’ as a meaningful patient‐focused outcome in Alzheimer’s disease: Qualitative concept elicitation and cognitive debriefing of the Dependence Scale in early symptomatic AD
Findings support patient dependence as a meaningful concept in AD and provide evidence supporting content validity of the DS. Most DS concepts were discussed during the interviews. Rater guidance is relevant and may mitigate the impact of perceived ambiguities in item phrasing.
Authors
- Laure Delbecque
- Yaakov Stern (ORCID: https://orcid.org/0000-0001-7542-3241)
- Stefan Cano (ORCID: https://orcid.org/0000-0001-9390-273X)
- Emma Elliott (ORCID: https://orcid.org/0000-0002-4323-9308)
- Phoebe Heinrich
- Alexandra S. Atkins
Institutions
- Eli Lilly (United States) (US)
- University of Manchester (GB)
- Cheltenham Festivals (GB)
- Columbia University (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1002/alz.084624
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00