Cortical thinning and Cognition in Cerebral Small Vessel Disease
In vivo MRI-derived measures for cerebral arteriolosclerosis are associated with global and lobar cortical thinning. The association between ARTS and cognition is partially mediated by cortical thinning. Findings suggest that cerebral small vessel disease may contribute to neurodegeneration and, both directly and indirectly, to subsequent cognitive impairment.
Authors
- Melissa Lamar (ORCID: https://orcid.org/0000-0001-6130-5543)
- David Alan Bennett (ORCID: https://orcid.org/0000-0003-3689-554X)
- Julie A. Schneider (ORCID: https://orcid.org/0000-0002-9482-1752)
- Alifiya Kapasi (ORCID: https://orcid.org/0000-0003-1911-8482)
- Konstantinos Arfanakis (ORCID: https://orcid.org/0000-0001-9705-597X)
- Arnold M Evia (ORCID: https://orcid.org/0000-0003-2262-890X)
- Sue E. Leurgans (ORCID: https://orcid.org/0000-0003-2536-1665)
- Maude Wagner (ORCID: https://orcid.org/0000-0002-1834-3218)
Institutions
- Rush University Medical Center (US)
- Rush University (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1002/alz.086495
- Primary Topic
- Cerebrovascular and Carotid Artery Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00