Large‐scale Genome‐wide Investigation of Short Tandem Repeats Associated with Alzheimer’s Disease Risk

Our first biallelic STR GWAS results demonstrate the power of our approach, and together with the complementary subsequent analyses (e.g., multiallelic length-based STR GWAS method, conditional analyses, e/sSTR integration analyses, and additional replication and meta-analyses), it has the potential to unravel and characterize AD-associated STRs, towards a full characterization of all types of understudied genetic variation for AD in the future.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2024-12-01
DOI
https://doi.org/10.1002/alz.091344
Primary Topic
Genetic Associations and Epidemiology
Type
article
Field-Weighted Citation Impact
0.00
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article

Large‐scale Genome‐wide Investigation of Short Tandem Repeats Associated with Alzheimer’s Disease Risk

Kristel Sleegers, Fahri Küçükali
Alzheimer s & Dementia
Genetic Associations and Epidemiology
article

Large‐scale Genome‐wide Investigation of Short Tandem Repeats Associated with Alzheimer’s Disease Risk

Kristel Sleegers, Fahri Küçükali
article en

Abstract

Our first biallelic STR GWAS results demonstrate the power of our approach, and together with the complementary subsequent analyses (e.g., multiallelic length-based STR GWAS method, conditional analyses, e/sSTR integration analyses, and additional replication and meta-analyses), it has the potential to unravel and characterize AD-associated STRs, towards a full characterization of all types of understudied genetic variation for AD in the future.

Alzheimer s & DementiaVol. 20(S1)
University of Antwerp (BE), VIB-UAntwerp Center for Molecular Neurology (BE)
Openalex Percentile: Top 73%
Genetic Associations and Epidemiology
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