Propionate Decreases Microglial Activation and Alters Phagocytic Machinery in Response to Aggregated Amyloid Beta <i>in vitro</i>

Altogether, our data demonstrate a modulatory role of propionate on microglia that may dampen immune activation in response to Aβ and potentially improve AD pathogenesis.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2024-12-01
DOI
https://doi.org/10.1002/alz.087578
Primary Topic
Neuroinflammation and Neurodegeneration Mechanisms
Type
article
Field-Weighted Citation Impact
0.00
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article

Propionate Decreases Microglial Activation and Alters Phagocytic Machinery in Response to Aggregated Amyloid Beta in vitro

Jiangjiang Zhu, Andrew Gold
1 links
Alzheimer s & Dementia
Neuroinflammation and Neurodegeneration Mechanisms
article

Propionate Decreases Microglial Activation and Alters Phagocytic Machinery in Response to Aggregated Amyloid Beta in vitro

Jiangjiang Zhu, Andrew Gold
article en

Abstract

Altogether, our data demonstrate a modulatory role of propionate on microglia that may dampen immune activation in response to Aβ and potentially improve AD pathogenesis.

Alzheimer s & DementiaVol. 20(S1)
The Ohio State University (US)
Openalex Percentile: Top 72%
Neuroinflammation and Neurodegeneration Mechanisms
DOIOpen Access PDFOpenAlex
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Propionate Decreases Microglial Activation and Alters Phagocytic Machinery in Response to Aggregated Amyloid Beta <i>in vitro</i> — Jiangjiang Zhu, Andrew Gold · Alzheimer s & Dementia (2024) | TGRS Research Map | TGRS