DCTclock metrics differentiate between amnestic and vascular mild cognitive impairment
Metrics derived from the process of DCTclock performance, especially those obtained during the copy clock condition, showed utility for differentiating between vascular and amnestic MCI. Comparing cognitive phenotypes at the early stage of MCI is arguably a more difficult task than comparing those phenotypes among individuals who have progressed to dementia and thus exhibit more pronounced signs of cognitive impairment. More data from individuals with such cognitive profiles are needed for building robust ML models that can differentiate among MCI subtypes with higher accuracy.
Authors
- Brian W. Haas (ORCID: https://orcid.org/0000-0002-6860-448X)
- David W. Bates (ORCID: https://orcid.org/0000-0001-6268-1540)
- Ali Jannati (ORCID: https://orcid.org/0000-0003-0826-1275)
- John Showalter (ORCID: https://orcid.org/0009-0002-6290-9589)
- Álvaro Pascual‐Leone (ORCID: https://orcid.org/0000-0001-8975-0382)
- Sean Tobyne (ORCID: https://orcid.org/0000-0001-5985-7920)
Institutions
- Harvard University (US)
- Hebrew SeniorLife (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1002/alz.089745
- Citations
- 1
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.39