The associations between <i>CYP19A1</i> polymorphisms and serum 17ß‐estradiol levels in Chinese patients with Alzheimer’s disease
In conclusion, our findings suggest a novel link between CYP19A1 polymorphisms and variation of serum 17ß-estradiol levels in Chinese elderly. This novel evidence may reflect inter-individual differences of estrogen exposure according to different CYP19A1 genotypes during aging and dementia process. Our findings may highlight a new perspective to understand the underlying mechanisms of AD.
Authors
- Yanhui Fan (ORCID: https://orcid.org/0000-0001-9677-3777)
- Lu Hua Chen (ORCID: https://orcid.org/0000-0002-3959-0226)
- Leung‐Wing Chu (ORCID: https://orcid.org/0000-0002-9066-2811)
- You‐Qiang Song (ORCID: https://orcid.org/0000-0001-9407-2256)
Institutions
- Hong Kong Polytechnic University (HK)
- Chinese University of Hong Kong (HK)
- Chinese Academy of Sciences (CN)
- Institute of Computing Technology (CN)
- University of Hong Kong (HK)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1002/alz.086088
- Primary Topic
- Estrogen and related hormone effects
- Type
- article
- Field-Weighted Citation Impact
- 0.00