The impact of knowledge of β‐amyloid PET scan result on cognitive test performance: results of the REVEAL‐SCAN study
Knowledge of an elevated amyloid result reduced cognitively unimpaired persons PACC scores. A greater impact was observed in Black/African American participants' test performance compared to non-Black participants. In contrast, knowledge of not-elevated amyloid showed no impact on test performance in any of the groups. Clinical trials should consider the potential impact of AD biomarker knowledge on cognitive outcomes.
Authors
- Kathleen A. Welsh‐Bohmer (ORCID: https://orcid.org/0000-0003-1824-0179)
- J. Scott Roberts
- Jason Karlawish (ORCID: https://orcid.org/0000-0002-6880-2865)
- Allyson Gregoire
- Kristin Harkins (ORCID: https://orcid.org/0000-0001-5360-1043)
- Jonathan M. Reader (ORCID: https://orcid.org/0000-0002-3245-9196)
- Kelly M. Bakulski (ORCID: https://orcid.org/0000-0002-9605-6337)
- Subhamoy Pal (ORCID: https://orcid.org/0000-0003-0133-8444)
- Robert C. Green (ORCID: https://orcid.org/0009-0001-3252-711X)
Institutions
- Brigham and Women's Hospital (US)
- University of Michigan (US)
- Duke Medical Center (US)
- University of Pennsylvania (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1002/alz.089271
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00