Theta band optogenetic stimulation of the septo‐hippocampal fibres in the fornix reduces interictal spikes and rescues memory performance in hAPP‐j20 mice
These data validate theta band optical stimulation as a viable method to pace the septo-hippocampal network effectively reducing IS events and recovering memory performance in an APP mouse model.
Authors
- Eva Vico Varela (ORCID: https://orcid.org/0000-0002-0279-1569)
- Sylvain Williams (ORCID: https://orcid.org/0000-0002-2511-0631)
- Guillaume Etter (ORCID: https://orcid.org/0000-0001-6417-901X)
- James E. Carmichael (ORCID: https://orcid.org/0000-0001-5218-804X)
- Frédéric Manseau (ORCID: https://orcid.org/0000-0003-3725-9561)
- Jisoo Choi (ORCID: https://orcid.org/0000-0003-4464-1048)
Institutions
- MaineGeneral Medical Center (US)
- McGill University (CA)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1002/alz.088106
- Primary Topic
- Photoreceptor and optogenetics research
- Type
- article
- Field-Weighted Citation Impact
- 0.00