Long-term complete remission of two patients with synchronous liver metastasis from pancreatic cancer and underlying BRCA-2 mutation

Germline testing for BRCA is important in PDAC because it influences treatment choices that impact survival. Complete responses with chemotherapy alone are rarely observed in metastatic PDAC, but may be seen upon treatment with platinum-based therapy.

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Publication Details

Journal
Acta Gastro Enterologica Belgica
Published
2024-12-01
DOI
https://doi.org/10.51821/87.4.11787
Primary Topic
Pancreatic and Hepatic Oncology Research
Type
article
Field-Weighted Citation Impact
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article

Long-term complete remission of two patients with synchronous liver metastasis from pancreatic cancer and underlying BRCA-2 mutation

Anne Hoorens, K. Kortbeek, Nathalie Van Heddeghem, L Crapé et al.
1 links
Acta Gastro Enterologica Belgica
Pancreatic and Hepatic Oncology Research
article

Long-term complete remission of two patients with synchronous liver metastasis from pancreatic cancer and underlying BRCA-2 mutation

Anne Hoorens, K. Kortbeek, Nathalie Van Heddeghem, L Crapé, Frederik Berrevoet, Eline Naert, Karel Geboes, S. Ribeiro
article en

Abstract

Germline testing for BRCA is important in PDAC because it influences treatment choices that impact survival. Complete responses with chemotherapy alone are rarely observed in metastatic PDAC, but may be seen upon treatment with platinum-based therapy.

Acta Gastro Enterologica BelgicaVol. 87(4)
HOGENT University of Applied Sciences and Arts (BE), Ghent University Hospital (BE), Statistics Belgium (BE), Ghent University (BE), Onze Lieve Vrouwziekenhuis Hospital (BE)
No poverty
Openalex Percentile: Top 58%
Pancreatic and Hepatic Oncology Research
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Long-term complete remission of two patients with synchronous liver metastasis from pancreatic cancer and underlying BRCA-2 mutation — Anne Hoorens, K. Kortbeek, et al. · Acta Gastro Enterologica Belgica (2024) | TGRS Research Map | TGRS