[Reversal Roles and Its Mechanism of Asiatic Acid on Multidrug Resistance in K562/ADR Cells Through the Wnt/β-catenin Pathway].
AA inhibits K562/ADR cell proliferation in a concentration-dependent manner and reverse their resistance to ADR, the reversal mechanism may be related to the down-regulation of MRP1 and P-gp expression after inhibiting Wnt/β-catenin signaling pathway.
Authors
- Xinyu Zhou (ORCID: https://orcid.org/0000-0003-1908-0357)
- Yang Liu (ORCID: https://orcid.org/0009-0002-2379-6323)
- Lei Zhang (ORCID: https://orcid.org/0000-0003-3638-6219)
- Ting Zhang (ORCID: https://orcid.org/0000-0001-6896-6088)
- Xiu-hong Jia
Institutions
- Shandong University of Aeronautics (CN)
Publication Details
- Journal
- PubMed
- Published
- 2024-12-01
- DOI
- https://doi.org/10.19746/j.cnki.issn.1009-2137.2024.06.010
- Citations
- 2
- Primary Topic
- Medicinal Plants and Neuroprotection
- Type
- article