[Curcumol Mediates the Programmed Cell Death in Acute Myeloid Leukemia through PI3K/AKT Signaling Pathway].
Curcumol may mediate the programmed death of AML cells by inhibiting the PI3K/AKT signaling pathway, affecting the expression of Bcl-2 family proteins, and promoting the activation of core members of Caspase family, so as to play an anti-leukemia role.
Authors
- Yan-Quan Liu
- Gareth Leng (ORCID: https://orcid.org/0000-0002-2388-8466)
- Ling Guo (ORCID: https://orcid.org/0000-0003-1155-6170)
- Hai-Liang Li (ORCID: https://orcid.org/0000-0002-4497-5649)
- Zhuoyu Li (ORCID: https://orcid.org/0009-0006-9858-6733)
- Yili Wang (ORCID: https://orcid.org/0000-0002-8772-0005)
- Xiaoyun Chen
Institutions
- Guangdong Medical College (CN)
- Dongguan People’s Hospital (CN)
- First Affiliated Hospital of Gannan Medical University (CN)
Publication Details
- Journal
- PubMed
- Published
- 2024-12-01
- DOI
- https://doi.org/10.19746/j.cnki.issn.1009-2137.2024.06.008
- Primary Topic
- Curcumin's Biomedical Applications
- Type
- article