[Influence of Methylenetetrahydrofolate Reductase <i>C677T</i> Polymorphism on High-Dose Methotrexate Toxicity in Pediatric Mature B-cell lymphoma Patients].
The risk of developing oral mucositis in children with mature B-cell lymphoma is associated with plasma MTX concentration. Polymorphism of <i>MTHFR C677T</i> gene is not related to plasma MTX concentration in children with mature B-cell lymphoma, but is related to grade III to IV hematological toxicity.
Authors
- Feifei Sun (ORCID: https://orcid.org/0000-0001-9539-1451)
- Suying Lü (ORCID: https://orcid.org/0000-0001-8117-3533)
- Junting Huang (ORCID: https://orcid.org/0000-0002-2448-5837)
- Jia Zhu
- Zijun Zhen (ORCID: https://orcid.org/0000-0002-4442-0897)
- B. A. Shi (ORCID: https://orcid.org/0009-0008-2479-6783)
- Yizhuo Zhang (ORCID: https://orcid.org/0000-0002-6128-3476)
- Juan Wang (ORCID: https://orcid.org/0009-0008-2350-6836)
- Lan-Ying Guo
- Jiaqian Xu (ORCID: https://orcid.org/0000-0002-5218-2710)
- Xiao-Fei Sun
- Yanpeng Wu
Institutions
- Sun Yat-sen University (CN)
- Sun Yat-sen University Cancer Center (CN)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- PubMed
- Published
- 2024-12-01
- DOI
- https://doi.org/10.19746/j.cnki.issn.1009-2137.2024.06.015
- Primary Topic
- Folate and B Vitamins Research
- Type
- article