[Genetic Mutation Profile and Risk Stratification of Cytogenetically Normal Acute Myeloid Leukemia with <i><i>CEBPA-bZIP</i></i> Mutations Based on Multi-Gene Sequencing].

Adult CN-AML with <i>CEBPA-bZIP</i> mutation has a complex co-mutation pattern. The nomogram model based on mutations of <i>CFS3R, KMT2A</i> and DNA methylation-related genes together with WBC count can further divide this subset of patients into a relatively low-risk group and a relatively high-risk group. For individuals in the high-risk group, allo-HSCT is proposed as post-remission therapy. The above data will benefit the prognosis estimation and treatment decision for adult CN-AML with <i>CEBPA-bZIP</i> mutation.