[The Impact of <i>SRSF1</i> -Mediated Alternative Splicing of <i>RBBP6</i> on the Proliferation of Multiple Myeloma Cells].
In MM, splicing factor <i>SRSF1</i> can cause alternative splicing abnormalities in <i>RBBP6</i> . The <i>RBBP6</i> isoform 1 promotes MM cell proliferation, while the <i>RBBP6</i> isoform 3 inhibits MM cell proliferation, and the mechanism may be related to regulating the p53 pathway.
Authors
- Sha Song (ORCID: https://orcid.org/0000-0002-5096-6669)
- Wenzhuo Zhuang (ORCID: https://orcid.org/0000-0002-8552-991X)
- Bing-Zong Li (ORCID: https://orcid.org/0000-0002-2732-9354)
- Weimin Zhang (ORCID: https://orcid.org/0000-0002-8836-1438)
Institutions
- Soochow University (CN)
- Second Affiliated Hospital of Soochow University (CN)
Publication Details
- Journal
- PubMed
- Published
- 2024-12-01
- DOI
- https://doi.org/10.19746/j.cnki.issn.1009-2137.2024.06.016
- Primary Topic
- Cancer-related Molecular Pathways
- Type
- article