Redefining skin health: The potential of plant-based bakuchiol as a sustainable substitute for retinoids

Background: The skin structure alters with age, leading to a decrease in collagen and diminished elasticity of the skin. While retinol proves to be an excellent anti-aging solution, its side effects prompt the search for gentler alternatives. This study evaluates bakuchiol’s effectiveness and safety compared to traditional retinoids. Material and Methods: A thorough literature review was performed using PubMed and Google Scholar, employing keywords related to the topic. Results: Recent studies highlight bakuchiol’s efficacy in reducing wrinkles and hyperpigmentation, with better tolerability than retinol. It is also under investigation for better skin penetration and collagen production. Comparatively, bakuchiol and retinol show significant anti-aging effects, yet bakuchiol’s additional antioxidative properties and the lack of side effects present it as a promising skincare ingredient. Conclusions: Bakuchiol offers a natural, effective retinol alternative, matching its rejuvenating effects with enhanced antioxidant benefits. Its superior tolerance makes it suitable for sensitive skin. While promising, further research is needed to fully grasp bakuchiol’s long-term benefits and confirm its role in skincare. Key words: Retinol, Retinoids, Bakuchiol, Skin, Photoaging