Metabolic Dysfunction-associated Steatotic Liver Disease–related Hepatocellular Carcinoma: Current Research Insights

exhibit one of five cardiometabolic risk factors (CMRFs): overweight/obesity, prediabetes/diabetes, prehypertension/ hypertension, hypertriglyceridemia, and low high-density lipoprotein cholesterol levels [3,4].Recent studies have reported that MASLD almost directly replaces NAFLD, with more than 95% of patients with NAFLD meeting the criteria for MASLD [5,6].The new nomenclature is expected to improve the assessment of clinical features and disease prognosis through its focus on CMRFs.In this article, we therefore review the recent research on MASLD-related HCC, such as epidemiology, risk factors with a particular focus on CMRFs in light of the new nomenclature, surveillance strategies, and risk stratification models.