Phytochemistry, GC-MS analysis of Acacia nilotica fruits and Moringa oleifera leaves and their Antibacterial activity on Escherichia coli and Staphylococcus aureus local strains

Antibiotics are bacteria-control agents used to inhibit or kill bacterial cells and most of their alternative sources are the natural products. The aim of this work was to study the phytochemical composition of Acacia nilotica fruits and Moringa oleifera leaves and their antibacterial effects on E. coli and Staphylococcus aureus. The dried powders of the selected plant materials were prepared to determine the main phytochemicals, the GC-MS analysis and to estimate the inhibitory effects against the selected bacterial strains through disc diffusion method. The results showed that, M. oleifera contained flavonoids, saponnins and terpenoids, as same as A. nilotica which included also glycosides and tannins. The main compound from A. nilotica fruits was (1,2,3-Benzenetriol compound was the main component; 85.11%), while that of M. oleifera leaves was (1,3-propanediol, 2-(hydroxymethyl)-2nitro-; 13.68%). Also, E. coli was relatively more susceptible to A. nilotica fruits extract than M. oleifera leave, but M. oleifera leaves show promising alternative to penicillin. S. aureus was relatively more susceptibility to M. oleifera leave than A. nilotica fruits and penicillin than E. coli local strain. More pharmaceutical investigation on these plant parts should be done in order to get maximum benefit of these products to control different bacterial strains.