Profile of Rheumatoid Factor in Pregnant Women at the University Hospital Center for Mother and Child (Chu-Me)

Introduction: Rheumatoid Arthritis (RA) is the most common chronic inflammatory rheumatism, predominantly affecting women. The general objective of our study is to contribute to the management of pregnant women with RA at CHU-ME in N'Djamena. Materials and Methods: This prospective study analyzed the Rheumatoid Factor (Latex Test) in 60 parturients at the prenatal consultation (CPN) of CHU-ME from January 1st to March 31st, 2024. The serological analysis of the RF was determined by an agglutination test on a slide. The variables studied were sociodemographic, clinical, and biological. Results were expressed in average, percentage with standard deviation. Results: Out of 60 samples analyzed, we identified 3 cases of RF positivity in pregnant women showing a rate of 5%. The average age of parturients was 22 years old, ranging from 18 to 40. Most pregnant women had a secondary education level (40%), and 91.66% resided in urban areas. Multiparous women represented 75%, from whom most of them shows no clinical signs (60%) or medical history (91.66%). Conclusion: RF is a preventive factor against the progression to more severe stages of RA, contributing to the reduction of prenatal mortality risks.