Vulnerability of Blood Type “A” to Coronavirus Delta Strain

Background: The precise correlation between blood grouping and the affinity of corona-virus for infection still is indecisive. Using blood grouping kits (ABO) the susceptibility of blood groupings to coronavirus pandemic was investigated in 894 patients from both genders (507 male and 387 female) positive victims admitted state hospitals and/or kept in quarantine at Mosul province, Iraq for the period of (February 1st 2020-January 31st 2022. Results: The results revealed that infection in type “A” blood group was significantly (p≤0.05-0.01) (42.6%) higher than other groups followed by type “B” (27.8%), type “AB” (15.6%) and type “O” groups (13.8%). Conclusion: It is concluded that blood type “A” is the most vulnerable for infection to the virus than other types due to affinity of the Delta strain coronavirus in attaching extra cell membrane receptors in antigen-A erythrocytes according to key and lock concept, or due to sweet molecule contents of receptors due to the presence of a favorite antibody-b in blood serum of type “A” could serve as additional receptors to the virus that may act as a part of innate immune response to neutralize viral particles in comparison with other blood groups.