A relationship study between different parameters and standardized uptake values of normal liver by using positron emission tomography / computed tomography scan

Background: Integrated Positron Emission Tomography (PET) is widely used to diagnose, stage, and track human diseases during whole-body scanning.Standardized uptake values (SUV max ) of normal organs were evaluated by Fluorlne-18-Fluoro-2-doxyD-glucose [ 18 F-FDG (PET/CT)] scanning.Multimodality imaging is an interesting area of research that aims to study the relationship between SUV max in normal livers and different parameters determined with PET/CT.Materials and Methods: A total of 100 people were tested for 18 F-FDG PET/CT.All participants fasted for at least 6 hours before PET/CT imaging, and their fasting blood glucose levels were normal.Scans were acquired following an intravenous dose of 18 F-FDG, and PET scans were collected 45-90 minutes after FDG injection.We measured the SUV max in the livers of persons with normal BMI, high BMI, and obesity.Results: After adjusting each SUV max based on the results of the BMI calculation, which were determined for each subject based on their height and weight, the relationship between SUV max and BMI was statistically significant (p value < 0.05).The SUV measurement was greater in males than females, and it increased significantly in both male and female overweight and obese patients.Gender and BMI were the most reliable independent predictors of SUV value. Conclusion:The hepatic absorption of 18 FFDG increases with the patient's BMI.Patients' genders are the independent variables that best predict their hepatic SUV values.

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Publication Details

Journal
International Journal of Radiation Research
Published
2024-10-01
DOI
https://doi.org/10.61186/ijrr.22.4.831
Primary Topic
Liver Disease Diagnosis and Treatment
Type
article
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article

A relationship study between different parameters and standardized uptake values of normal liver by using positron emission tomography / computed tomography scan

Mahmoud Abbas, Satar M. Kadam, Sinan Issa
International Journal of Radiation Research
Liver Disease Diagnosis and Treatment
article

A relationship study between different parameters and standardized uptake values of normal liver by using positron emission tomography / computed tomography scan

Mahmoud Abbas, Satar M. Kadam, Sinan Issa
article en

Abstract

Background: Integrated Positron Emission Tomography (PET) is widely used to diagnose, stage, and track human diseases during whole-body scanning.Standardized uptake values (SUV max ) of normal organs were evaluated by Fluorlne-18-Fluoro-2-doxyD-glucose [ 18 F-FDG (PET/CT)] scanning.Multimodality imaging is an interesting area of research that aims to study the relationship between SUV max in normal livers and different parameters determined with PET/CT.Materials and Methods: A total of 100 people were tested for 18 F-FDG PET/CT.All participants fasted for at least 6 hours before PET/CT imaging, and their fasting blood glucose levels were normal.Scans were acquired following an intravenous dose of 18 F-FDG, and PET scans were collected 45-90 minutes after FDG injection.We measured the SUV max in the livers of persons with normal BMI, high BMI, and obesity.Results: After adjusting each SUV max based on the results of the BMI calculation, which were determined for each subject based on their height and weight, the relationship between SUV max and BMI was statistically significant (p value < 0.05).The SUV measurement was greater in males than females, and it increased significantly in both male and female overweight and obese patients.Gender and BMI were the most reliable independent predictors of SUV value. Conclusion:The hepatic absorption of 18 FFDG increases with the patient's BMI.Patients' genders are the independent variables that best predict their hepatic SUV values.

International Journal of Radiation ResearchVol. 22(4)
University of Baghdad (IQ), Alsalam University College (IQ), Iraqi University (IQ)
Openalex Percentile: Top 63%
Liver Disease Diagnosis and Treatment
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A relationship study between different parameters and standardized uptake values of normal liver by using positron emission tomography / computed tomography scan — Mahmoud Abbas, Satar M. Kadam, et al. · International Journal of Radiation Research (2024) | TGRS Research Map | TGRS