Cone beam CT enhanced scan in evaluating the efficacy and prognosis of interventional chemoembolization and radiation for liver cancer

Background: This work analyzed the efficacy of Cone-Beam Computed Tomography (CBCT) enhanced scan in evaluating the therapeutic effect and prognosis of interventional therapy in patients with liver cancer (LC).Materials and Methods: Eighty-two individuals diagnosed with primary LC were enrolled here and grouped according to the intraoperative treatment.Patients in group A were only treated with digital subtraction angiography (DSA) during the operation, while those in group B received DSA and CBCT during the operation.The operation time, radiation dose, detection rate of tumor lesions, and lipiodol deposition were compared between two groups.Results: In group A, 54 lesions were identified before operation, 48 lesions during intraoperative angiography, and 6 lesions remained undetected.In group B, 57 LC lesions were identified before operation, and 57 lesions during intraoperative CBCT enhanced scan, and 2 small LC lesions not presented previously were detected.The number of lesions with complete lipiodol precipitation in group B (42) was clearly higher as against group A (32) (P < 0.05).The operation time of group B was clearly longer as against group A (P < 0.05), but there existed no substantial difference in radiation dose patients in different groups (P > 0.05).Conclusion: The results indicated that CBCT enhanced scan was superior to conventional DSA in detecting tumor lesions, nutrient arteries, and lipiodol deposition in patients undergoing LC chemoembolization.Importantly, this enhanced method did not increase radiation dose but prolonged the operation time.