Anesthetic Management for Dental Procedures and Oral Surgery in a Patient with Cornelia de Lange Syndrome: A Case Report

Cornelia de Lange syndrome (CdLS) is a rare genetic disease of multiple malformations affecting the craniofacial, musculoskeletal, neurosensory, gastrointestinal, central nervous, cardiovascular, and genitourinary systems. CdLS patients may often require more than one high-risk anesthesia procedure, and due to the difficulties encountered in this syndrome, it is challenging for the anesthesiologist and important strategies are required in order to be successful in anesthesia management. We present the report on the successful anesthetic management of a 21-year-old woman with CdLS who underwent extensive dental procedures and oral surgery. The procedure was performed under general anesthesia by inhaling volatile gases due to the lack of intravenous (IV) access.