3D Printing Model of Limbic System: A Novel Mode of Visualising Neuroanatomy for Undergraduate Medical Students

Introduction: Three-dimensional (3D) printing of anatomical structures at rapid rate using Magnetic Resonance Imaging (MRI) and Computerized Tomography (CT) data is widely utilized in modern era. Due to accurate restoration of complicated anatomical systems, 3D printing is increasingly being used in medicine, from fundamental anatomy through surgical practice and sophisticated research applications. No precise 3D printed limbic system models that focus on Neuroanatomy education are available. The present study was undertaken to generate scientifically accurate 3D model of the limbic system of the human brain from MRI scan data and 3D printing of the same for medical education / applications. Methods: MRI scanned data of the brain of unknown adult patient was obtained from the department of radiodiagnosis with approval of Medical Record Department. The general process involved to create the physical model of limbic system from original imaging data can be divided into four steps. i) Image data acquisition, ii) Image processing, iii) 3D printing and iv) Post-processing. Results: A three-dimensional printed model of the limbic system that depicts various components of the system was successfully created. All the structures shown in the 3D digital model were accurately generated in physical model. A single limbic system model print takes 5-6 hours using specific settings on the given printer (Ultimaker S5). The weights of the 3D printed limbic system model, including supports prior to removal, are roughly 190-220g at the specified settings Conclusion: This 3D model would be helpful for spatial visualization of the various structures comprising the limbic system.